Scientific References

The Science of UA.01: Clinical Research & Mitochondrial Studies
Mitophagy & Cellular Maintenance
Analysis of Urolithin A regarding mitochondrial markers and cellular signaling
Nature Metabolism
2019
A human clinical study observing the correlation between Urolithin A, mitophagy induction, and mitochondrial gene expression in an adult demographic.‡
Mitochondrial Density Research
Pyrroloquinoline quinone (PQQ) and its role in the PGC-1α pathway
Journal of Biological Chemistry (JBC)
2010
This landmark study on how PQQ works as a catalyst for the PGC-1α pathway.‡
Cellular Energy Infrastructure
Coenzyme Q10: Review of biological transport roles
Journal of Evidence-Based Integrative Medicine
2011
A comprehensive review regarding the role of CoQ10 in the Electron Transport Chain and the natural biological conversion of nutrients into ATP.‡
Research on Physical Resilience
Evaluation of Urolithin A regarding muscle endurance and mitochondrial markers
Cell Reports Medicine
2022
A randomized, double-blind trial evaluating the correlation between daily Urolithin A administration and mitochondrial health markers in an adult demographic.‡
Mitochondrial Structural Research
Analysis of Pyrroloquinoline Quinone (PQQ) and mitochondrial integrity
Current Research in Food Science
2024
Research examining PQQ in relation to mitochondrial structural integrity and its role within the Electron Transport Chain and respiratory complex activity.‡
Cellular Maintenance Signaling
Foundational study on Urolithin A and mitophagy induction
Nature Medicine
2016
Foundational research investigating Urolithin A’s role in biological signaling and the natural recycling processes associated with cellular maintenance.‡
Support for Physical Resilience
Analysis of Coenzyme Q10 regarding energy levels during physical demand
Nutrition
2008
A double-blind study evaluating how CoQ10 correlates with physical resilience and the maintenance of healthy energy levels.‡
PQQ and Mitochondrial Maintenance
Research on Pyrroloquinoline quinone (PQQ) and mitochondrial quantity
Nutrition Reviews
2008
Scientific review examining PQQ as a nutrient that correlates with mitochondrial quantity and biological function.‡
Mitochondrial Network Integrity
Study on PGC-1α and mitochondrial properties in relation to exercise
American Journal of Physiology-Endocrinology and Metabolism
2019
Research examining the role of PGC-1α in supporting the structural integrity of mitochondrial networks over time.‡
Cellular Chronology Research
Review of mitochondrial function over time
Biochimica et Biophysica Acta (BBA)
1996
A foundational scientific review examining the natural changes in mitochondrial function and the research surrounding systemic cellular maintenance.‡
The following studies relate to the individual ingredients (Urolithin A, CoQ10, PQQ) and are provided for educational purposes only. These studies do not necessarily represent the results of the UA.01 finished product. This content is not intended as medical advice.